Sophomore Sara Hammond had the biggest game, while sophomore Jude Schimmel scored the biggest basket of the night as the University of Louisville women's basketball team scored a 47-45 victory on opening night.
The No. 9 Cardinals got a layup with 24 seconds left by Jude Schimmel for the game-winning layup after a steal.
Texas A&M missed two shots in the final seconds.
"That steal at the end of the game is nothing that surprised me," U of L coach Jeff Walz said. "(Schimmel) does it in practice. She's very deceptive. She looks frail, she looks tiny out there, and then boom she steps in the passing lane on an inbounds play and comes up with the biggest play of the game."
Hammond finished the game with 20 points and 13 rebounds. She was 9 of 18 from the field and added three steals.
"I was really excited for Sara," Walz said. "She has really put in the work."
Senior Monique Reid added 10 points in 13 minutes of her first game since a season-ending knee injury last December. Shoni Schimmel added eight points, four assists, two steals and two rebounds.
U of L shot 21 of 53 from the field, including just 2 of 12 three-pointers.
Texas A&M, ranked No. 15 in the first AP poll, was the 2011 national champions. The Aggies beat U of L early last season.
"This is what is all about," Texas A&M coach Gary Bair said. "I like playing Jeff (Walz) and I like playing his team. I respect them and his program he has built. It is good to see the Louisvilles, the Marylands, and the Texas A&Ms up at the top, instead of the normal big four or five. I mean we got some good players.
"You all draw a bigger crowd than some of those I named. You all should be proud of what you have here. You have a great fan base and great promotion hopefully we can keep this series going. I enjoy coming here, and I think he enjoyed coming to our place."